Comparative Study on the Biodegradation Behavior of Pure Mg in NaCl Solution and Simulated Body Fluids

Voleti Sri Sai Harsha Vardhan; Ambuj Sharma; Sathish Tiruveedhula; Ratna Sunil Buradagunta

doi:10.4028/p-grwes4

Paper Titles

Characterization of CP-Ti Processed by Micro Arc Oxidation for Bone Implant Applications
p.35

Investigations on Wear and Friction Characteristics of AA-2024/MOS₂/Al₂O₃ HMMCs
p.41

Particulate Based AZ91 Magnesium Hybrid Composites – A Short Review
p.51

Developing Mg Based Composites for Degradable Orthopedic Implant Applications: A Review
p.61

Comparative Study on the Biodegradation Behavior of Pure Mg in NaCl Solution and Simulated Body Fluids
p.69

Micro Structural and Hardness Study of Al 6065 and CaSiO₃ Composite with Stir Casting Route
p.75

Analysis of Functionally Graded Cylinders Subjected to Internal Pressure
p.81

Optimization of Time, Part Accuracy and Surface Roughness of TI-6AL-4V Processed through SLM
p.93

Experimental Investigation of Optimization of Machining Parameters in Abrasive Water Jet Machining
p.101

HomeAdvances in Science and TechnologyAdvances in Science and Technology Vol. 120Comparative Study on the Biodegradation Behavior...

Comparative Study on the Biodegradation Behavior of Pure Mg in NaCl Solution and Simulated Body Fluids

Abstract:

Developing Mg based implants for temporary applications based on their biodegradation in the physiological environment is a potential research area in the biomedical engineering. Assessing the bio-corrosion in simulated conditions helps to reduce the complexity of research studies associated with in-vivo experiments and can be used to assess the true behavior of the Mg implant in artificial solutions. On the other hand, assessing the corrosion behavior by using 3.5% NaCl solution is a standard ASTM protocol widely used in the industries. Hence, in the present work, degradation of pure Mg due to bio-corrosion in two different solutions i.e simulated body fluids (SBF) and 3.5% NaCl solution has been investigated. From the results, the weight loss measurements indicated higher degradation during the initial 24 h in SBF solution. However, with the increased immersion time to 72 h, due to the deposition of mineral phases from SBF as confirmed from the electron microscopy and X-Ray diffraction study, the degradation was observed as decreased in SBF compared with NaCl solution. Hence, the results demonstrate that the evaluation of degradation behavior of Mg based materials in simulated physiological environments is appropriate compared with the standard NaCl environment.

You might also be interested in these eBooks

Mechanical Engineering and Emerging Technologies

View Preview

Info:

Periodical:

Advances in Science and Technology (Volume 120)

Pages:

69-73

DOI:

https://doi.org/10.4028/p-grwes4

Citation:

Cite this paper

Online since:

September 2022

Authors:

Voleti Sri Sai Harsha Vardhan, Ambuj Sharma, Sathish Tiruveedhula, Ratna Sunil Buradagunta*

Keywords:

Biodegradation, Bone Implants, Corrosion, Magnesium, NaCl, SBF

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

* - Corresponding Author

References

[1] F. Witte, N.Hort, C. Vogt, et al. Degradable biomaterials based on magnesium corrosion. CurrOpin Solid St Mater Sci.12 (2008)63–72.

Google Scholar

[2] R. Zeng, W. Dietzel, F. Witte, et al. Progress and challenge for magnesium alloys as biomaterials. Adv Eng Mater.10(8) (2008) B3–B14.

DOI: 10.1002/adem.200800035

Google Scholar

[3] N. T. Kirkland, N. Birbilis. Magnesium biomaterials design, testing, and best practice. Springer New York, USA (2014).

Google Scholar

[4] M. M. Jamel, H. F. Lopez, Designing Advanced Biomedical Biodegradable Mg Alloys: A Review. Metals12 (2022) 85.

DOI: 10.3390/met12010085

Google Scholar

[5] S. Agarwal, J. Curtin, B. Duffy, S. Jaiswal, Biodegradable magnesium alloys for orthopaedic applications: A review on corrosion, biocompatibility and surface modifications,Mater. Sci. Eng. C68 (2016) 948–963.

DOI: 10.1016/j.msec.2016.06.020

Google Scholar

[6] Y. Yang et al, Mg bone implant: Features, developments and prospective, Mater. Des. 185 (2020) 108259.

Google Scholar

[7] A. Cuneyt Tas, The use of physiological solutions or media in calcium phosphate synthesis and processing, Acta Biomater. 10 (2014) 1771–1792.

DOI: 10.1016/j.actbio.2013.12.047

Google Scholar

[8] ASTM Standard G31-72. Standard practice for laboratory immersion corrosion testing of metals. West Conshohocken, PA: ASTM International (2004).

Google Scholar

[9] F. Witte, J. Fischer, J Nellesen, H-A Crostack, V. Kaese, A. Pisch, B. Felix, W. Henning, In vitro and in vivo corrosion measurements of magnesium alloys, Biomaterials 27 (2006) 1013–1018.

DOI: 10.1016/j.biomaterials.2005.07.037

Google Scholar

[10] Y. Chen, Z. Xu, Ch. Smith, J. Sankar,Recent advances on the development of magnesium alloys for biodegradable implants; Acta Biomater10(11) (2014) 4561-4573.

DOI: 10.1016/j.actbio.2014.07.005

Google Scholar

[11] T. Kokubo, H. Takadama, How useful is SBF in predicting in vivo bone bioactivity?, Biomaterials 27 (2006) 2907-2915.

DOI: 10.1016/j.biomaterials.2006.01.017

Google Scholar

[12] B. Ratna Sunil, T.S. Sampath Kumar, Uday Chakkingal, V. Nandakumar, Mukesh Doble, Nano-hydroxyapatite reinforced AZ31 magnesium alloy by friction stir processing: A solid state processing for biodegradable metal matrix composites, J Mater Sci: Mater Med, 25 (2014) 975–988.

DOI: 10.1007/s10856-013-5127-7

Google Scholar

[13] Y. Wang, M. Wei, J. Gao, J. Hu, Y. Zhang, Corrosion process of pure magnesium in simulated body fluid, Mater. Lett. 62 (2008) 2181–2184.

DOI: 10.1016/j.matlet.2007.11.045

Google Scholar

[14] B. Ratna Sunil, T.S. Sampath Kumar, Uday Chakkingal, V. Nandakumar, Mukesh Doble, Friction stir processing of magnesium – nanohydroxyapatite composites with controlled in vitro degradation ehaviour, Mater Sci Eng C, 39 (2014) 315–324.

DOI: 10.1016/j.msec.2014.03.004

Google Scholar