MCM-41 /PCL Coated Hydroxyapatite and its Application to Drug Delivery System

Abstract:

Article Preview

Porous hydroxyapatite coated with MCM-41/PCL has been utilized as the matrix for controlled drug delivery. SEM result shows porous hydroxyapatite block is formed of three dimensionally inter-connected pores of 250 –300 *m in size, similar to human cancellous bone. TEM observation confirms the pore size of MCM-41 scatters about 50 Å. Ibuprofen was loaded into the pores of MCM-41 and hybridized with polycaprolactone to coat on the surface of hydroxyapatite block and controlled release profiles were studied by soaking the samples in a simulated body fluid using a UV-VIS spectrophotometer.

Info:

Periodical:

Key Engineering Materials (Volumes 309-311)

Main Theme:

Edited by:

Takashi Nakamura, Kimihiro Yamashita and Masashi Neo

Pages:

911-914

DOI:

10.4028/www.scientific.net/KEM.309-311.911

Citation:

Y. Kim et al., "MCM-41 /PCL Coated Hydroxyapatite and its Application to Drug Delivery System ", Key Engineering Materials, Vols. 309-311, pp. 911-914, 2006

Online since:

May 2006

Export:

Price:

$35.00

In order to see related information, you need to Login.

In order to see related information, you need to Login.