Innovative Technique for the Preparation of Porous Bilayer Hydroxyapatite/Chitosan Scaffolds for Osteochondral Applications

Abstract:

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In this study, it is shown that it is possible to develop 3D-porous bilayer hydroxyapatite/chitosan scaffolds by means of combining a sintering and a freeze-drying technique. Scanning electron microscopy (SEM/EDS) studies revealed that the scaffolds possess a well-defined orientation and anisotropic porosity, with pore size ranging between 50-350 µm. Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) patterns evidenced the formation of crystalline hydroxyapatite. Moreover, the compression tests revealed that these scaffolds have adequate mechanical properties for being used in tissue engineering of osteochondral defects.

Info:

Periodical:

Key Engineering Materials (Volumes 309-311)

Main Theme:

Edited by:

Takashi Nakamura, Kimihiro Yamashita and Masashi Neo

Pages:

927-930

DOI:

10.4028/www.scientific.net/KEM.309-311.927

Citation:

J. M. Oliveira et al., "Innovative Technique for the Preparation of Porous Bilayer Hydroxyapatite/Chitosan Scaffolds for Osteochondral Applications", Key Engineering Materials, Vols. 309-311, pp. 927-930, 2006

Online since:

May 2006

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Price:

$35.00

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