Comparing Adsorptive Property of Natural and Synthesized Hydroxyapatite to Albumin, Fibrinogen and IgG

Xiao Ying Lü; Huang Yan; Bu Zhong Zheng; Ai Ping Wu

doi:10.4028/www.scientific.net/KEM.330-332.869

Paper Titles

The Effect of Lif-Maleic Acid Added Calcium Aluminate Bone Cement and Ca-PMMA Composite Bone Cement on Bone Regeneration in Rat Calvarial Defects
p.851

Control of Protein Initial Burst from Zinc-Hydroxyapatite / Poly(L-Lactide) System
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Contribution of Surface Charge to Bovine Serum Albumin Adsorption on Hydroxyapatite Ceramic Particles
p.861

Covalent Immobilization of Heparin on Anatase TiO₂ Films via Chemical Adsorbent Phosphoric Acid Interface
p.865

Comparing Adsorptive Property of Natural and Synthesized Hydroxyapatite to Albumin, Fibrinogen and IgG
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The Synthesis and Initial Studying Anticoagulant Property of O-Doped DLC Films by DC-MFCVAD
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Surface Wettability Enhances Osteoblast Adhesion on Silicon-Substituted Hydroxyapatite Thin Films
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Effect of Mn on Protein Adsorption on Mn-TCP/FHA Coatings
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Effect of Pamidronate on Protein Adsorption and Osteoblast Adhesion to Hydroxyapatite Bioceramics Scaffold
p.885

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Comparing Adsorptive Property of Natural and Synthesized Hydroxyapatite to Albumin, Fibrinogen and IgG

Abstract:

The aim of this study was to compare the plasma protein adsorptive property of the natural hydroxyapatite (HA) and the synthesized HA to human albumin (Alb), fibrinogen (Fib) and immunoglobulin G (IgG). Different methods such as reflectometry interference spectroscopy (RIfS) measuring, Fourier transform infrared spectroscopy (FTIR) analysis and weighing assessment were used to measure the adsorbed amount of Alb, Fib and IgG on the natural HA and the synthesized HA. To compare the adsorptive property of protein adsorbed on these two kinds of materials, the ratio of Alb/Fib (RA/F) and the ratio of Alb/IgG (RA/I) were calculated. The results from all three methods showed that the values of RA/F and RA/I obtained with natural HA were smaller than those obtained with synthesized HA, that indicated that the natural HA adsorbed more human fibrinogen than human albumin and thas it would enhance blood coagulation and in favor of bone repairing.