Mechanical Performance and In Vitro Studies of Hydroxyapatite/Wollastonite Scaffold for Bone Tissue Engineering

Abstract:

A highly porous (~90%) interconnected hydroxyapatite/wollastonite (HA/WS) scaffolds were prepared by polymeric sponge replica method using a slurry containing HA:Calcium silicate in the weight ratio of 50:50 and sintered at 1300 °C. The phase purity of the scaffolds were analyzed by using XRD. The pore size, pore structure, microstructure and elemental analysis of the scaffolds before and after SBF soaking were analyzed using SEM and EDS. In-vitro bioactivity and bioresorbability confirmed the feasibility of the developed scaffolds. The HA/WS scaffold shows two fold increase in the compressive strength compared to pure HA scaffold.

• Periodical: Key Engineering Materials (Volumes 493-494)
• Pages: 855-860
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.493-494.855
• Online since: October 2011
• Authors: Sanosh Kunjalukkal Padmanabhan, Marina Carrozzo, Francesca Gervaso, Francesca Scalera, Alessandro Sannino, Antonio Licciulli
• Keywords: Bioactivity, Bioceramic, Biodegradability, Scaffold, Sintering

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