Simplification of the Synthesis Method for Silicon-Substituted Hydroxyapatite: A Raman Spectroscopy Study

Abstract:

The addition of silicon ions to hydroxyapatite (HA) provides a more inorganic bone-like chemical composition compared to stoichiometric HA. It is known to aid the bioactivity of the material and to improve the rates of osseointegration, osteoconduction and bone mineralisation. The literature, however, lacks detailed information regarding each step of the aqueous precipitation procedure to produce silicon-substituted HA (Si-HA). The current work utilised Raman spectroscopy at each stage of the aqueous precipitation method to determine how the silicate is incorporated into the HA structure when producing Si-HA. Raman spectra indicated that at the initial stages of the reaction the disilicate ion (Si₂O₇^6-) formed with the orthosilicate (SiO₄^4-) ion becoming more dominant after sintering. The results demonstrated that the form of silicate in the Si-HA aqueous precipitation method can be tracked using Raman spectroscopy.

• Periodical: Key Engineering Materials (Volumes 529-530)
• Pages: 94-99
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.529-530.94
• Online since: November 2012
• Authors: F.J. Harden, Iain R. Gibson, J.M.S. Skakle
• Keywords: Hydroxyapatite (HAP), Raman Spectroscopy, Silicate, Silicon-Substituted Hydroxyapatite, X-Ray Powder Diffraction

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