Use of Silver Nanoparticles in Treatment of Socially Significant Diseases

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The effects of colloidal silver are determined by concentration, sizes and stability of the finely-divided nanoparticles. Studies of silver-based drugs acting against antibiotic-resistant microorganisms are of significant scientific and practical interest. Silver does not effect on the infection, but directly on the cell structure. The main disadvantages of the current nanosilver-based compositions include low aggregative stability, polydispersity and oxidation of silver nanoparticles during prolonged storage. The main attention should be paid to the preservation of activity and bioavailability of the active substance, and ideally the increase in efficiency through synergy with other components of the formulation. Scientists of different special fields should focus not only on the development of new technologies for production of new nanomedicines, but on the possible health and environmental side effects

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February 2016

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[1] I. Ignatov, O.V. Mosin, Methods for the preparation of finely-divided nanoparticles of colloidal silver, Naukovedenie (in Russian). 22 (2014) available at http: /naukovedenie. ru/PDF/85TVN314. pdf.

Google Scholar

[2] S. Subarani, S. Sabhanayakam, C. Kamaraj, Studies on the impact of biosynthesized silver nanoparticles (AgNPs) in relation to malaria and filariasis vector control against Anopheles stephensi Liston and Culex quinquefasciatus Say (Diptera: Culicidae), Parasitol Res. 112 (2013).

DOI: 10.1007/s00436-012-3158-5

Google Scholar

[3] D.S. Savchenko, Study of genotoxicity and cytotoxicity of nanocomposite of finely-dispersed silica with silver nanoparticles, J. of New Med. Technol. (in Russian). 20 (2013) 44-47.

Google Scholar

[4] G.M. Shub, O.G. Shapoval, S. Ye. Velmakin, L.B. Sakulina, Changing of adhesive activity of Eschrichiacoli and Pseudomonasaeruginosa under the influence of silver nanoparticles, Fundamental Research (in Russian). 6 (2013) 1453-1455.

Google Scholar

[5] O. Brandt, M. Mildner, A. E. Egger, M. Groessl, U. Rix, M. Posch, B. K. Keppler, C. Strupp, B. Mueller, G. Stingl, Nanoscalic silver possesses broad-spectrum antimicrobial activities and exhibits fewer toxicological side effects than silver sulfadiazine, Nanomedicine–UK. 8 (2012).

DOI: 10.1016/j.nano.2011.07.005

Google Scholar

[6] M.S. Islam, C. Larimer, A. Ojha, I. Nettleship, Antimycobacterial efficacy of silver nanoparticles as deposited on porous membrane filters, Mater. Sci. Eng. C. Mater. Biol. Appl. 33 (2013) 4575-4581.

DOI: 10.1016/j.msec.2013.07.013

Google Scholar

[7] F. Martínez-Gutiérrez, J.M. Guajardo-Pacheco, M.E. Noriega-Trevino, E.P. Thi, N. Reiner, E. Orrantia, Y. Av-Gay, F. Ruiz, H. Bach, Antimicrobial activity, cytotoxicity and inflammatory response of novel plastics embedded with silver nanoparticles, Future Microbiol. 8 (2013).

DOI: 10.2217/fmb.13.5

Google Scholar

[8] Ye.M. Yegorova, Biochemical synthesis of gold and zinc nanoparticles in reverse micelles, J Phys Chem. (in Russian) 84 (2010) 713-720.

Google Scholar

[9] N.B. Demina, S.A. Skatkov, Pharmaceutical nanotechnology: development of technological disciplines in higher pharmaceutical education, Farmatsiya (in Russian) 2 (2009) 46-50.

Google Scholar

[10] Z. Marková, K.M. Šišková, J. Filip, J. Cuda, M. Kolar, K. Safarova, I. Medrik, R. Zboril, Air Stable Magnetic Bimetallic Fe–Ag Nanoparticles for Advanced Antimicrobial Treatment and Phosphorus Removal, Future Microbiol. 47 (2013) 5285-5293.

DOI: 10.1021/es304693g

Google Scholar

[11] N. Chen, Y. Zheng, J. Yin, X. Li, C. Zheng, Inhibitory effects of silver nanoparticles against adenovirus type 3 in vitro, J. Virol. Methods. 193 (2013) 470-477.

DOI: 10.1016/j.jviromet.2013.07.020

Google Scholar

[12] V. Ye. Borisenko, Influence of nanosized particles on biological objects, Meditsina: theoretical and practical reviewed medical journal in Belarus (in Russian) 1 (2010) 39-43.

Google Scholar

[13] L.S. Sosenkova, Ye.M. Yegorova, Small silver nanoparticles for studies of biological effects, J Phys Chem. (in Russian) 85 (2011) 1-10.

Google Scholar

[14] M.V. Samsonova, Nanomedicine: current approaches to diagnostics and treatment of diseases, safety issues, Pulmonology (in Russian). 5 (2008) 5-13.

Google Scholar

[15] V.S. Ulashchik, Physiotherapy; Nanoparticles and nanotechnology in medicine, Zdravookhraneniye (in Russian). 2 (2009) 4-10.

Google Scholar

[16] F.A. Mohammed, Z. Ao, M. Girilal, L. Chen, X. Xiao, P. Kalaichelvan, X. Yao, Inactivation of microbial infectiousness by silver nanoparticles-coated condom: a new approach to inhibit HIV- and HSV-transmitted infection, Int. J. Nanomedicine. 7 (2012).

DOI: 10.2147/ijn.s34973

Google Scholar

[17] G. Rajakumar, A. Rahuman, Larvicidal activity of synthesized silver nanoparticles using Ecliptaprostrata leaf extract against filariasis and malaria vectors, Acta Trop. 118 (2011) 196-203.

DOI: 10.1016/j.actatropica.2011.03.003

Google Scholar

[18] G.G. Onishchenko, V.V. Kutyrev, D.V. Utkin, Legal and theoretical conditions for application of nanotechnology and nanomaterials in diagnostics, prevention and treatment of dangerous infectious diseases, Journal of Microbiology Epidemiology and Immunobiology. 6 (2008).

Google Scholar

[19] R.B. Salunkhe, S.V. Patil, C.D. Patil, B.K. Salunke, Larvicidal potential of silver nanoparticles synthesized using fungus Cochlioboluslunatus against Aedesaegypti (Linnaeus, 1762) and Anopheles stephensi Liston (Diptera; Culicidae), Parasitol. Res. 109 (2011).

DOI: 10.1007/s00436-011-2328-1

Google Scholar

[20] V.A. Zverev, Health Nanotechnology, J. of New Med. Technol. (in Russian) 15 (2008) 161-162.

Google Scholar

[21] L. Rizzello, P.P. Pompa, Nanosilver-based antibacterial drugs and devices: mechanisms, methodological drawbacks, and guidelines, Chem. Soc. Rev. 43 (2014) 1501-1518.

DOI: 10.1039/c3cs60218d

Google Scholar

[22] L.N. Shirokova, V.A. Aleksandrova, Ye.M. Yegorova, G.A. Vikhoreva, Macromolecular systems and bactericidal film based on a derivative of chitin and silver nanoparticles, Appl Biochem. Micro+. (in Russian) 45 (2009) 422-426.

Google Scholar

[23] V.A. Kosolapov, A.A. Spasov, Prospects and problems of nanopharmacology, Journal of Volgograd State Medical University (in Russian). 4 (2009) 12-16.

Google Scholar

[24] P.K. Jain, I.H. El-Sayed, M.A. El-Sayed, Au nanoparticles target cancer, Nano Today. 2 (2007) 18-29.

DOI: 10.1016/s1748-0132(07)70016-6

Google Scholar

[25] R. Singh, P. Wagh, S. Wadhwani, S. Gaidhani, A. Kumbhar, J. Bellare, B.A. Chopade, Synthesis, optimization, and characterization of silver nanoparticles from Acinetobactercalcoaceticus and their enhanced antibacterial activity when combined with antibiotics, Int. J. Nanomed. 8 (2013).

DOI: 10.2147/ijn.s48913

Google Scholar

[26] V.G. Gorokhov, Nanotechnology – a new paradigm of scientific and technical thought, Higher Education Today (in Russian). 5 (2008) 36-41.

Google Scholar

[27] M.A. Paltsev, Nanotechnology in clinical medicine and pharmacy, Terapevt. (in Russian) 4 (2009) 20-26.

Google Scholar

[28] S. Galdiero, A. Falanga, M. Vitiello, M. Cantisani, V. Marra, M. Galdiero, Silver nanoparticles as potential antiviral agents, Molecules. 16 (2011) 8894-8918.

DOI: 10.3390/molecules16108894

Google Scholar

[29] K. Markowska, A.M. Grudniak, K.I. Wolska, Silver nanoparticles as an alternative strategy against bacterial biofilms, ActaBiochim. Pol. 60 (2013) 523-530.

DOI: 10.18388/abp.2013_2016

Google Scholar

[30] K.T.V. Chaitanya, Y. Muralidhar, P.E. Prasad, T.N. Prasad, M. Alpha Raj, Evaluation of therapeutic potential of nanosilver particles synthesised using aloin in experimental murine mastitis model, IET Nanobiotechnol. 7 (2013) 78-82.

DOI: 10.1049/iet-nbt.2012.0045

Google Scholar

[31] S. Gurunathan, J.W. Han, D.N. Kwon, J.H. Kim, Enhanced antibacterial and anti-biofilm activities of silver nanoparticles against Gram-negative and Gram-positive bacteria, Nanoscale Res Lett. 31 (2014) 373-379.

DOI: 10.1186/1556-276x-9-373

Google Scholar

[32] P. Jena, S. Mohanty, R. Mallick, B. Jacob, A. Sonawane, Toxicity and antibacterial assessment of chitosan-coated silver nanoparticles on human pathogens and macrophage cells, Int. J. Nanomedicine. 7 (2012) 1805-1818.

DOI: 10.2147/ijn.s28077

Google Scholar

[33] S.K. Singh, K. Goswami, R.D. Sharma, M.V. Reddy, D. Dash, Novel microfilaricidal activity of nanosilver, Int. J. Nanomedicine. 7 (2012) 1023-1030.

DOI: 10.2147/ijn.s28758

Google Scholar

[34] M. Rai, K. Kon K, A. Ingle, N. Duran, S. Galdiero, M. Galdiero, Broad-spectrum bioactivities of silver nanoparticles: the emerging trends and future prospects, Appl. Microbiol. Biot. 98 (2014) 1951-(1961).

DOI: 10.1007/s00253-013-5473-x

Google Scholar

[35] B.T. Glukhenkyi, V.I. Stepanenko, T.S. Konovalova, R.L. Stepanenko, I.N. Yurkova, V.I. Ryabushko, Yu.S. Bugaeva, N.A. Parhomenko, Experience of clinical application of the new drug Argoderm, (gel), containing silver nanoparticles, in comprehensive treatment of some skin diseases and urethritis, Ukrainian Journal of Dermatology, Venereology, Cosmetology (in Russian) 41 (2011).

Google Scholar