Electric Field Distribution around the Deep Brain Stimulation Electrode Inferred from Dielectric Measurements

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Abstract:

Information about the spatial distribution of the electric field can be obtained by measuring the electrode impedance as a function of the diameter of the electrolyte surrounding the electrode. The non-uniform distribution of the electric field around the electrode is supported by the variation of the geometry factor (GF) with the electrical conductivity and geometry of the volume conductor. A comparison of the values obtained for the GF from experimental data, from model calculations and simulations help to understand the non-uniform distribution of the electric field. The GF calculated from four-electrode-measurements is significantly higher. GF should be used with caution in calculations of the deep brain stimulation (DBS) electrode impedance.

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Materials Science Forum (Volumes 730-732)

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26-31

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November 2012

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© 2013 Trans Tech Publications Ltd. All Rights Reserved

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[1] R. J. Coffrey, Artificial Organs, 33(3) (2008) 208-220.

Google Scholar

[2] P. Limousin and I. Martinez-Torres, Neurotherapeutics 5 (2008) 309–19.

Google Scholar

[3] J. L. Ostrem and P. A. Starr, Neurotherapeutics 5 (2008) 320–30.

Google Scholar

[4] L. Ackermans, Y. Temel and V. Visser-Vandewalle, Neurotherapeutics, 5 (2008) 339–44.

Google Scholar

[5] S. Miocinovic, S. F. Lempka, G. S. Russo, C. B. Maks, C. R. Butson, K. E. Sakaie, J. L. Vitek and C. C. McIntyre, Exp. Neurol .216 (2009) 166–76.

DOI: 10.1016/j.expneurol.2008.11.024

Google Scholar

[6] P. F. Grant and M, M. Lowery, Medical Engineering & Physics 31 (2009) 1095–1103.

Google Scholar

[7] X. F. Wei and W. M. Grill, J. Neural Eng. 2 (2005) 139–47.

Google Scholar

[8] A. M. Kuncel and W. M. Grill, Clinuical Neurophysiology, 115 (2004) 2431-2441.

Google Scholar

[9] N. Yousif, R. Bayford, S. Wang and X. Liu, X, Neuroscience 152 (2008) 683–691.

Google Scholar

[10] C. R. Butson, C. B. Maks and C. C. McIntyre, Clin. Neurophysiol. 117 (2008) 447–54.

Google Scholar

[11] H. P. Schwan, in Physical Techniques in Biological Research, edited by L. Nastuk, Academic, New York, 1963, Chap. 6, p.323.

Google Scholar

[12] E. Vinter, S. Petersen, J. Gimsa, U. van Rienen, Proc. COMSOL Conference, 2009 Milan.

Google Scholar