Fabrication of Cu Nanowires and its Effect on Proliferation of Mesenchymal Stem Cells

Yuan Hui Song; Yang Ju; Lan Zhang; Yasuyuki Morita; Guan Bin Song

doi:10.4028/www.scientific.net/MSF.750.56

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Fabrication of Cu Nanowires and its Effect on Proliferation of Mesenchymal Stem Cells
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HomeMaterials Science ForumMaterials Science Forum Vol. 750Fabrication of Cu Nanowires and its Effect on...

Fabrication of Cu Nanowires and its Effect on Proliferation of Mesenchymal Stem Cells

Abstract:

Many studies have focused on the fabrication of Cu nanowires, because of their potential applications in diverse fields such as nanoelectronics and gene delivery. In this study, we successfully fabricated Cu nanowires by electrochemical deposition method. Cu nanowires was synthesized by electroplating from a 0.4M CuSO₄ bath, and the current was 0.005A. The length of nanowires can be controlled via deposition time and current. After depositing for 60 minutes, the length of the nanowires is approximately 10 µm. Serum coated and non-coated nanowires with the concentration of 10², 10³, 10⁴ and 10⁵ were added to 96-well cell culture plate in which mesenchymal stem cells were pre-seeded. After incubating for 3 days, cytotoxicity of nanowires was measured with MTT assay method. Results indicated that cytotoxicity increased as the increase of nanowires concentration. Serum coated nanowires had higher cell viability as compared with the non-coated group.

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Materials Science Forum (Volume 750)

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56-59

DOI:

https://doi.org/10.4028/www.scientific.net/MSF.750.56

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Online since:

March 2013

Authors:

Yuan Hui Song, Yang Ju, Lan Zhang, Yasuyuki Morita, Guan Bin Song

Keywords:

Cu Nanowires, Cytotoxicity, Electrochemical Deposition, Mesenchymal Stem Cells, Proliferation

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