Preparation and Properties Characterization of Modified Chitosan Composited Hemostatic Materials

Abstract:

Carboxymethyl chitosan (CAS) was obtained by carboxymethylation of chitosan (CS).The Ag⁺-CAS,TiO₂-CAS and Ag⁺-TiO₂-CAS were prepared by introducing AgNO₃ and nanometre TiO₂ solution into the product obtained the previous step. The structures of samples were characterized by IR, XRD, SEM etc. The properties of cruor and hemostasis were studied by biological experiment. The results showed that there were characteristic absorption peaks of carboxymethyl chitosan sodium salt around 3423cm^-1 and 1380cm^-1 in the IR spectra of modified carboxymethyl chitosan. The XRD showed it was metals Crystalline. The average diameter of CAS was about 14.8nm, the Ag⁺ was 143.5nm, nanometre TiO₂ was 267.2nm and all of them were homodisperse. The properties of crour and hemostasis of Ag⁺-TiO₂-CAS were superior to Ag⁺-CAS and TiO₂-CAS, while the Ag⁺-CAS and TiO₂-CAS were also have an advantage over CAS.

• Periodical: Materials Science Forum (Volume 852)
• Pages: 1271-1276
• DOI: https://doi.org/10.4028/www.scientific.net/MSF.852.1271
• Online since: April 2016
• Authors: Feng Ming Wang, Chang Ping Wei, Jing Li, Shuang Sun, Li Dan Dong, Qin Yi Liu
• Keywords: Carboxymethyl Chitosan, Characteristic, Composites, Performance, Preparation

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