Advanced Materials Research Vols. 989-994

Abstract: To explore the effect of crude polysaccharides of Dioscorea bulbifera L. (DBLP) on liver organs in mice bearing cervical cancer, the effects of DBLP on the liver weight in vivo, sections of liver were examined. Glutamate pyruvate transaminase (GPT) and Glutamic oxalo acetic Transaminase (GOT) activites of blood serum in tumor-bearing mice were detected by the colorimetric method. Superoxide dismutase (SOD) and Glutathione reductase (GR) of hepatic tissues were also determined by means of colorimetric method. Our results showed that the liver index, GPT and GOT activities of blood serum, SOD and GR activities of hepatic tissues of DBLP groups were almost the same as that of negative groups. however, the liver index, GPT and GOT activities of blood serum were decreased in DBLP groups compared to CTX groups. And the SOD and GR activities of hepatic tissues of DBLP groups were higher than that of CTX groups. These results demonstrated that DBLP had no effect on liver organs in mice bearing cervical cancer. These data would be a foundation for the appication of DBLP in antitumor, which indicated that DBLP would be a potential antitumor drug. And the further studies, such as antioxidant, should be developed.

Abstract: Two sorafenib analogs (9a,9b) containing sulfonylurea unit were synthesized and their chemical structures were confirmed by 1H NMR and MS spectrum. The synthesized compounds were evaluated for the inhibition rate against VEGFR2 kinase at 10μM level. The inhibition rates of compound 9a and 9b against VEGFR2 kinase were 61.0±11.1% and 22.6±2.6%, respectively. The results showed that the introduction of sulfonylurea unit is favorable for the activity, and further study is being carried out.

Abstract: Films of chitosan (Ch), Ch+0.5%(v/v) the citral (CI), Ch+2.5%(w/v) the citral β-cyclodextrin inclusion complex (β-CD-CI) and the physics mixture CI and β-CD-CI were prepared on the quality of fresh beef during refrigerated storage at 4±1°C were investigated, and verified the preservation effect of wrap fresh beef. The control and the treated beef samples were analyzed periodically for the total volatile basic nitrogen (TVBN), aerobic bacterial count (ABC), the sensory evaluation, and pH. The results indicate that all treatments retarded the decay of the beef samples. The chitosan film with the β-CD-CI exhibited superior to the preservation ability compared with control pure chitosan film treatment in maintaining the quality of fresh beef samples and significantly extended the shelf life by approximately 5 days.

Abstract: New antitumor strategies are underway and play important roles in clinical trials for combating cancer in future. Eucheuma gelatinae contains a certain amount of polysaccharides, which has various biological activities. In this study, the antitumor effect of Eucheuma gelatinae polysaccharide on murine H22 tumor bearing mice has been investigated. Histological stain, flow cytometry and other methods are applied to evaluate the effects of Eucheuma gelatinae polysaccharide on immunocompetence in vivo. The data indicates that Eucheuma gelatinae polysaccharide has antitumor effect in vivo by enhancing immunocompetence of the tumor bearers.

Abstract: A simple and sensitive ultra-performance convergence chromatography system coupled with a diode array detector for analysis of paclitaxel, 10-deacetyl-7-epipaclitaxel and cephalomannine in paclitaxel injection was developed. The analyses were carried out on a Waters Acquity UPC² BEH 2-EP using the mobile phase of mixture of supercritical CO₂ and methanol with a linear gradient elution from 92:8 to 82:18 at 50 °C. The method offers good linearity, higher resolution, and good repeatability. LOD and LOQ were 0.45 and 1.32 ng, respectively.

Abstract: In the experiment, a systematic study on the genotoxicity of organic extracts of the water in a reservoir at wet season and dry season. And the study was done by using comet assay. The study was to appraise the waters qualities after every treatment step from the view of the DNA damages on the mouse spleen lymphocytes. The results of the experiment can provide reliable basis for adjusting the treatment reasonably to purify raw water of different qualities.

Abstract: To deal with the power shortage of the implantable radio-telemetry system for animal physiological parameters dictation, a wireless power transmission system based on electromagnetic induction is proposed. The parameters of the couple coils are optimized considering the safety and stability of this power transmission, transmitting coil of rectangle section solenoid and three-dimensional receiving coil are selected. Experiments show that at least 150mW power could pick up on the load in a volume of Φ10.5 mm×11 mm with a transmission efficiency of 2.56%. Vivisection experiments verified the feasibility of the integrated radio-telemetry system based on this power supply technology.

Abstract: s. This paper uses alcohol thermal method, takes the mixed solution of N,N-two DMF and ethanol as solvent, in particular concentration of copper nitrate, prepares composite photocatalyst Cu/Cu₂O by control of temperature, then investigates the composite with XRD. The experimental results show that, the catalyst prepared has good dispersing, its average particle size is 7.96nm, and Cu comes into the Cu₂O lattice conducted the corresponding lattice distortions. In the 40W tungsten lamp irradiation, the photocatalyst can achieve effective degradation of traditional Chinese medicine wastewater, whose degradation rate can reach 97.3% and the COD removal rate can reach 95.6%.

Abstract: Urinalysis is not only widely employed in medical diagnosis but also suitable for household daily monitoring of personal health conditions. However, current urinalysis methods and instruments require more professional knowledge, while the sampling and treatment of urine samples are manual and inconvenient. In this work, a new-concept automatic urinalysis system is proposed to provide personal urinalysis services for home users. The system forms an eco-friendly intelligent toilet, which is of great significances in the future healthcare network. The basic strategy is to design a fixed supporting platform and various disposable urinalysis lab-on-chips with great expansibility and high flexibility. The intelligent device has multiple functions of automatic urine sampling, rapid on-chip detecting, auto-decontaminating and personalized health information technology (HIT) supporting, thus to provide a low-cost solution of automatic urinalysis services for both inpatients in hospitals and home-users. The structure of the urinalysis system logically resembles the frame with fixed smart cellphones and various mobile application programs. Besides, a biological lighting module is also designed to harvest the energy in wasted urine by continuous culturing vibrio fischeri, a luminescent bacterium. The integrated urinalysis system could create the possibility of remote medical services for home users, and meanwhile generates a new branch in the field of microsystem, which is entitled as ‘HIT-oriented lab-on-chips’.

Abstract: In order to further improve the quality of medical image fusion,an improved medical image fusion method, based on nonsubsampled contourlet transform (NSCT),is proposed in the paper. A fusion rule based on the improved pulse coupled neural network (PCNN) is adopted in low frequency sub-band coefficient. Because human visual is more sensitive to all local region pixels instead of single pixel,it is more reasonable that the region information stimulates PCNN instead of single pixel. Each neuron of PCNN model is stimulated by the region spatial frequency of low frequency sub-band coefficient .Low frequency sub-band coefficient is determined by the times of firing. When choosing the bandpass directional sub-band coefficients, the directional characteristics of NSCT has been made best use of in the paper.A fusion rule based on sum-modified Laplacian is presented in bandpass directional sub-band cosfficients.The experiment results show that the proposed method can greatly improve the quality of fusion image compared with traditional fusion methods.