Key Engineering Materials Vols. 381-382

Abstract: We address the problem of measuring the refractive index of biological materials. We limit our analysis to the case of colloids and consider the use of common automatic critical-angle refractometers to measure their effective refractive index. We provide rough guidelines to when these refractometers will incur in large errors and alternative techniques should be used.

Abstract: A full field phase detection system for surface plasmon resonance (SPR) bio-sensor is presented. The phase difference variation between s and p polarization resulting from the SPR was detected by the polarization interferometry. In the polarization interferometry, the light reflected from the SPR sensor was divided into four phase quardrature parts by polarization components. By means of an algorithm similar to phase shifting interferometry, the phase distribution of SPR bio-sensor was obtained. We have successfully detected the phase difference variation with 0.07º resolution within 1×1 mm2 full field range. The corresponding detection limit of the refractive index change is about 1×10-7.

Abstract: The purpose of this study was to investigate the effect of vibration device in gas transfer rate for usage as intravenous lung assist device. Specific attention was focused on the effect of membrane vibration. Quantitative experimental measurements were performed to evaluate the performance of the device, and to identify membrane vibration dependence on hemolysis. Scaling analysis was then used to infer the dimensionless groups that correlate the performance of a vibrated hollow tube membrane oxygenator. The experimental design and procedure are then given for a device for assessing the effectiveness of membrane vibrations. This ILAD is used to provide some insight into how wall vibrations might enhance the performance of an intravascular lung assist device. The time and the frequency response of PVDF sensor were investigated through various frequencies in the ILAD. In these devices, the flow of blood and the source of oxygen were separated by a semipermeable membrane allows oxygen to diffuse into and out of the f1uid, respectively. The results of experiments have shown vibrating ILAD performs effectively.

Abstract: In this study, we attempts to develop a sensing method to detect mismatched DNA in order to diagnose cancer. The sensing method will be developed to use for early diagnosis of cancer. Thus, protein immobilization was applied on the surface of the sensor in order to facilitate the detection of mismatched DNA. This method was designed to achieve the Ni-His-Tag to selectively bond with MutS, which has a covalent bond with the His-Tag, by using Ni-NTA. This method is troublesome because it involves a number of repeated composition processes. This method need gold surface to immobilize NTA (nitrotriamino acid). But this process is very complicated and expensive cost. Therefore, we try to immobilize NTA using PMMA (poly methyl methacrylate) polymer in this research to improve this method. In this study revealed that we could directly immobilize the NTA to the PMMA substrate not used Gold substrate. Also, we could directly immobilize the MutS to the NTA using the EDC solution. In addition, we can expect that the mismatched DNA can be detected from the results.

Abstract: This study is about the underlying conjugation mechanism between carbon nanotube and biomolecule by molecular dynamics. In order to know about the conjugation mechanism between carbon nanotube and biomolecule, molecular dynamics simulation between carbon nanotube and water molecules was taken first and then molecular dynamics simulation between biomolecules and water molecules was taken. At simulation between carbon nanotube and water molecules, kinetic energy and potential energy became decreased with time and it means that the distance between carbon nanotube and water molecules becomes distant with time by van der Waals force and hydrophobic force. Simulation results between biomolecules and water molecules are also same as the results of carbon nanotube and water molecules simulation. From these two simulations, the conjugation mechanism between carbon nanotube and biomolecules can be predicted. Also, from simulation results between carbon nanotube and biomolecules, the distance between carbon nanotube and biomolecules becames close and it supports previous two simulation results. From these results, we can know that biomolecules enter into the carbon nanotube's cavity because of van der Waals force and hydrophobic force.

Abstract: Infrared-based lie detection experiment methodology can open the human life window (0.6µm-16µm) through which the body spontaneous or active infrared responding images be gathered and analyzed by spectrum scoring in features of geography and computation. These raw images mainly load the indirect physiological, biochemical or direct brain evidences of cognitive lie and truth. Aiming at the mimic play card test, three tests of lie detection based on the medium or near infrared spectrum (NIRS) in four kinds of spectrum analysis are discussed. The instruments include the lock-in phase amplifier of Stanford University, TTM (Thermal Texture Maps) in US patent, and self-made auricular point NIRS (Chinese Jiangsu appraisal certificate No. 1017). The subjects’ signals sampling positions are on glabella, brows, abdomen or auricular point Antitragus No. 2. The spectrum analysis methods utilize the self-built feature extraction algorithms, the wavelet microscopy, and the bispetrum in validities of 92%, 100%, 80% and 80%. The results support the lie-truth law of “truth be the baseline of lie detection in view of brain power” (the statistical finding from review of 3D-MRI lie-detection reports included our work, subjects n = 4) for making foundation to the future lie detection 3D-SoC design.

Abstract: The effectiveness of the visual feedback to improve ability with the sense and muscular strength of human in our bicycle system was quantitatively verified in our study. Experiments were performed to find the factors related to the training of equilibrium sense. The subjects consisted of young and the aged and the group of young people was compared against the group of the aged. We investigated three different training modes, non-visual feedback (NVF), visual feedback of the weight (VFW), and visual feedback of the center of pressure (VFC) and measured the riding time and speed, the weight shift, and the center of pressure (COP) for twenties and seventies. The results showed that the running capability of the young and the aged became much better after repeated training. In addition, it was found out that the ability to control postural balance and the capability of equilibrium sense were improved with the presentation of the visual feedback information. These results will be effective in the diagnosis of equilibrium sense and vestibular function with the aged.

Abstract: The capability of recognizing human facial expression plays an important role in advanced human-robot interaction development. Through recognizing facial expressions, a robot can interact with a user in a more natural and friendly manner. In this paper, we proposed a facial expression recognition system based on an embedded image processing platform to classify different facial expressions on-line in real time. A low-cost embedded vision system has been designed and realized for robotic applications using a CMOS image sensor and digital signal processor (DSP). The current design acquires thirty 640x480 image frames per second (30 fps). The proposed emotion recognition algorithm has been successfully implemented on the real-time vision system. Experimental results on a pet robot show that the robot can interact with a person in a responding manner. The developed image processing platform is effective for accelerating the recognition speed to 25 recognitions per second with an average on-line recognition rate of 74.4% for five facial expressions.

Abstract: In this paper, we present a method of measuring a freeform surface profile from a single image taken by a vision system consisting of a digital camera and a pattern projector. The measurement can be implemented without calibrating the camera’s parameters, provided that the intrinsic and extrinsic parameters of the projector are known. The method enables the camera to have much more adaptability for measuring a stationary or moving object with complex shape of surface.

Abstract: A flexible temperature sensor array and a scanning system are developed in this paper. A 16×16 temperature sensor array in a 25×20 mm2 area is fabricated on a flexible copper-PI substrate using MEMS fabrication technology. Platinum is employed as the temperature sensing material, which is often so called the resistance temperature detector (RTD). Copper patterns on both sides of the flexible substrate serve as the row and column interconnects for scanning circuitry. In each element of the temperature sensor array, the resistance of platinum, which is patterned by lift-off process, can be measured by the scanning system.